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In vivo chloride concentrations surge to proteotoxic levels during acid stress

To successfully colonize the intestine, bacteria must survive passage through the stomach. The permeability of the outer membrane renders the periplasm of Gram-negative bacteria vulnerable to stomach acid, which inactivates proteins. Here we report that the semipermeable nature of the outer membrane...

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Detalles Bibliográficos
Autores principales: Stull, Frederick, Hipp, Hannah, Stockbridge, Randy B., Bardwell, James C. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6193267/
https://www.ncbi.nlm.nih.gov/pubmed/30323217
http://dx.doi.org/10.1038/s41589-018-0143-z