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In vivo chloride concentrations surge to proteotoxic levels during acid stress
To successfully colonize the intestine, bacteria must survive passage through the stomach. The permeability of the outer membrane renders the periplasm of Gram-negative bacteria vulnerable to stomach acid, which inactivates proteins. Here we report that the semipermeable nature of the outer membrane...
Autores principales: | Stull, Frederick, Hipp, Hannah, Stockbridge, Randy B., Bardwell, James C. A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6193267/ https://www.ncbi.nlm.nih.gov/pubmed/30323217 http://dx.doi.org/10.1038/s41589-018-0143-z |
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