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Bupleurum chinense Roots: a Bioactivity-Guided Approach toward Saponin-Type NF- κ B Inhibitors

The roots of Bupleurum chinense have a long history in traditional medicine to treat infectious diseases and inflammatory disorders. Two major compounds, saikosaponins A and D, were reported to exert potent anti-inflammatory activity by inhibiting NF- κ B. In the present study, we isolated new saiko...

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Detalles Bibliográficos
Autores principales: Liu, Xin, Latkolik, Simone, Atanasov, Atanas G., Kunert, Olaf, Pferschy-Wenzig, Eva-Maria, Heiss, Elke H., Malainer, Clemens, Schinkovitz, Andreas, Kollroser, Manfred, Dirsch, Verena M., Bauer, Rudolf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Georg Thieme Verlag KG 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6193276/
https://www.ncbi.nlm.nih.gov/pubmed/28902374
http://dx.doi.org/10.1055/s-0043-118226