Transfection of Peripheral Blood Monocytes with SOX2 Enhances Multipotency, Proliferation, and Redifferentiation into Neohepatocytes and Insulin-Producing Cells

Following a several-day incubation in medium containing IL-3 and M-CSF to generate a more plastic intermediate “reprogrammed multipotent cells of monocytic origin (RMCMO),” peripheral blood mononuclear cells (PBMCs) can be efficiently converted to hepatocyte-like cells (neohepatocytes) and insulin-p...

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Detalles Bibliográficos
Autores principales: Hyder, Ayman, Ehnert, Sabrina, Fändrich, Fred, Ungefroren, Hendrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6193350/
https://www.ncbi.nlm.nih.gov/pubmed/30402109
http://dx.doi.org/10.1155/2018/4271875

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6193350/
https://www.ncbi.nlm.nih.gov/pubmed/30402109
http://dx.doi.org/10.1155/2018/4271875

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