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Dynamic Effects of Early Adolescent Stress on Depressive-Like Behaviors and Expression of Cytokines and JMJD3 in the Prefrontal Cortex and Hippocampus of Rats

Aims: Expression of inflammatory cytokines in the brain has been reported to be involved in the pathogenesis of and susceptibility to depression. Jumonji domain-containing 3 (Jmjd3), which is a histone H3 lysine 27 (H3K27) demethylase and can regulate microglial activation, has been regarded as a cr...

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Detalles Bibliográficos
Autores principales: Wang, Rui, Wang, Wei, Xu, Jingjing, Liu, Dexiang, Jiang, Hong, Pan, Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6193509/
https://www.ncbi.nlm.nih.gov/pubmed/30364220
http://dx.doi.org/10.3389/fpsyt.2018.00471