Direct measurement of transcription factor dissociation excludes a simple operator occupancy model for gene regulation

Transcription factors (TFs) mediate gene regulation by site specific binding to chromosomal operators. It is commonly assumed that the level of repression is given by the equilibrium binding of a repressor to its operator alone. However, this assumption has not been possible to test in living cells....

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Detalles Bibliográficos
Autores principales: Hammar, Petter, Walldén, Mats, Fange, David, Persson, Fredrik, Baltekin, Özden, Ullman, Gustaf, Leroy, Prune, Elf, Johan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6193529/
https://www.ncbi.nlm.nih.gov/pubmed/24562187
http://dx.doi.org/10.1038/ng.2905

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6193529/
https://www.ncbi.nlm.nih.gov/pubmed/24562187
http://dx.doi.org/10.1038/ng.2905

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