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Direct measurement of transcription factor dissociation excludes a simple operator occupancy model for gene regulation
Transcription factors (TFs) mediate gene regulation by site specific binding to chromosomal operators. It is commonly assumed that the level of repression is given by the equilibrium binding of a repressor to its operator alone. However, this assumption has not been possible to test in living cells....
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6193529/ https://www.ncbi.nlm.nih.gov/pubmed/24562187 http://dx.doi.org/10.1038/ng.2905 |