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Pairwise and higher order genetic interactions during the evolution of a tRNA

A central question in genetics and evolution is the extent to which mutations have outcomes that change depending on the genetic context in which they occur1–3. Pairwise interactions between mutations have been systematically mapped within4–18 and between19 genes, and contribute substantially to phe...

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Detalles Bibliográficos
Autores principales: Domingo, Júlia, Diss, Guillaume, Lehner, Ben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6193533/
https://www.ncbi.nlm.nih.gov/pubmed/29849145
http://dx.doi.org/10.1038/s41586-018-0170-7