Running in the wheel: Defining individual severity levels in mice

The fine-scale grading of the severity experienced by animals used in research constitutes a key element of the 3Rs (replace, reduce, and refine) principles and a legal requirement in the European Union Directive 2010/63/EU. Particularly, the exact assessment of all signs of pain, suffering, and dis...

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Detalles Bibliográficos
Autores principales: Häger, Christine, Keubler, Lydia M., Talbot, Steven R., Biernot, Svenja, Weegh, Nora, Buchheister, Stephanie, Buettner, Manuela, Glage, Silke, Bleich, André
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Methods and Resources
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6193607/
https://www.ncbi.nlm.nih.gov/pubmed/30335759
http://dx.doi.org/10.1371/journal.pbio.2006159

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6193607/
https://www.ncbi.nlm.nih.gov/pubmed/30335759
http://dx.doi.org/10.1371/journal.pbio.2006159

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