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Membrane localization of the Repeats-in-Toxin (RTX) Leukotoxin (LtxA) produced by Aggregatibacter actinomycetemcomitans

The oral bacterium, Aggregatibacter actinomycetemcomitans, which is associated with localized aggressive periodontitis, as well as systemic infections including endocarditis, produces numerous virulence factors, including a repeats-in-toxin (RTX) protein called leukotoxin (LtxA), which kills human i...

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Detalles Bibliográficos
Autores principales: Brown, Angela C., Boesze-Battaglia, Kathleen, Balashova, Nataliya V., Mas Gómez, Nestor, Speicher, Kaye, Tang, Hsin-Yao, Duszyk, Margaret E., Lally, Edward T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6193665/
https://www.ncbi.nlm.nih.gov/pubmed/30335797
http://dx.doi.org/10.1371/journal.pone.0205871