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Tyro3/Axl/Mertk-deficient mice develop bone marrow edema which is an early pathological marker in rheumatoid arthritis

Rheumatoid arthritis is an auto-immune disease of the synovial joints, hallmarked by chronic inflammation and subsequent progressive tissue destruction. TYRO3, AXL and MER (gene name Mertk) (TAM) receptors are part of a negative feedback signaling system in the immune reaction and mediate efferocyto...

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Detalles Bibliográficos
Autores principales: Waterborg, Claire E. J., Koenders, Marije I., van Lent, Peter L. E. M., van der Kraan, Peter M., van de Loo, Fons A. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6193696/
https://www.ncbi.nlm.nih.gov/pubmed/30335822
http://dx.doi.org/10.1371/journal.pone.0205902