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Lassa virus glycoprotein: stopping a moving target

The structure of a prefusion arenavirus GPC was enigmatic for many years, owing to the metastable and non-covalent nature of the association between the receptor binding and fusion subunits. Recent engineering efforts to stabilize the glycoprotein of the Old World arenavirus Lassa in a native, yet c...

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Detalles Bibliográficos
Autores principales: Hastie, Kathryn M, Saphire, Erica Ollmann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6193841/
https://www.ncbi.nlm.nih.gov/pubmed/29843991
http://dx.doi.org/10.1016/j.coviro.2018.05.002