Fingolimod reduces circulating tight-junction protein levels and in vitro peripheral blood mononuclear cells migration in multiple sclerosis patients

There are no data on the effects of fingolimod, an immunomodulatory drug used in treatment of multiple sclerosis (MS), on circulating tight-junction (TJ) protein levels as well as on peripheral blood mononuclear cells (PBMC) migration. Serum TJ protein [occludin (OCLN), claudin-5 (CLN-5) and zonula...

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Detalles Bibliográficos
Autores principales: Annunziata, Pasquale, Cioni, Chiara, Masi, Gianni, Tassi, Maristella, Marotta, Giuseppe, Severi, Sauro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6193926/
https://www.ncbi.nlm.nih.gov/pubmed/30337577
http://dx.doi.org/10.1038/s41598-018-33672-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6193926/
https://www.ncbi.nlm.nih.gov/pubmed/30337577
http://dx.doi.org/10.1038/s41598-018-33672-9

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