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Fingolimod reduces circulating tight-junction protein levels and in vitro peripheral blood mononuclear cells migration in multiple sclerosis patients
There are no data on the effects of fingolimod, an immunomodulatory drug used in treatment of multiple sclerosis (MS), on circulating tight-junction (TJ) protein levels as well as on peripheral blood mononuclear cells (PBMC) migration. Serum TJ protein [occludin (OCLN), claudin-5 (CLN-5) and zonula...
Autores principales: | Annunziata, Pasquale, Cioni, Chiara, Masi, Gianni, Tassi, Maristella, Marotta, Giuseppe, Severi, Sauro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6193926/ https://www.ncbi.nlm.nih.gov/pubmed/30337577 http://dx.doi.org/10.1038/s41598-018-33672-9 |
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