hMENA isoforms impact NSCLC patient outcome through fibronectin/β1 integrin axis

We demonstrated previously that the splicing of the actin regulator, hMENA, generates two alternatively expressed isoforms, hMENA(11a) and hMENAΔv6, which have opposite functions in cell invasiveness. Their mechanisms of action have remained unclear. Here we report two major findings: (i) hMENA regu...

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Detalles Bibliográficos
Autores principales: Di Modugno, Francesca, Spada, Sheila, Palermo, Belinda, Visca, Paolo, Iapicca, Pierluigi, Di Carlo, Anna, Antoniani, Barbara, Sperduti, Isabella, Di Benedetto, Anna, Terrenato, Irene, Mottolese, Marcella, Gandolfi, Francesco, Facciolo, Francesco, Chen, Emily I., Schwartz, Martin A., Santoni, Angela, Bissell, Mina J., Nisticò, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6193944/
https://www.ncbi.nlm.nih.gov/pubmed/29907768
http://dx.doi.org/10.1038/s41388-018-0364-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6193944/
https://www.ncbi.nlm.nih.gov/pubmed/29907768
http://dx.doi.org/10.1038/s41388-018-0364-3

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