A RNA producing DNA hydrogel as a platform for a high performance RNA interference system

RNA interference (RNAi) is a mechanism in which small interfering RNA (siRNA) silences a target gene. Herein, we describe a DNA hydrogel capable of producing siRNA and interfering with protein expression. This RNAi-exhibiting gel (termed I-gel for interfering gel) consists of a plasmid carrying the...

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Detalles Bibliográficos
Autores principales: Song, Jaejung, Lee, Minhyuk, Kim, Taeyoung, Na, Jeongkyeong, Jung, Yebin, Jung, Gyoo Yeol, Kim, Sungjee, Park, Nokyoung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6193956/
https://www.ncbi.nlm.nih.gov/pubmed/30337586
http://dx.doi.org/10.1038/s41467-018-06864-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6193956/
https://www.ncbi.nlm.nih.gov/pubmed/30337586
http://dx.doi.org/10.1038/s41467-018-06864-0

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