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Structure of MHC class I-like MILL2 reveals heparan-sulfate binding and interdomain flexibility

The MILL family, composed of MILL1 and MILL2, is a group of nonclassical MHC class I molecules that occur in some orders of mammals. It has been reported that mouse MILL2 is involved in wound healing; however, the molecular mechanisms remain unknown. Here, we determine the crystal structure of MILL2...

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Detalles Bibliográficos
Autores principales: Kajikawa, Mizuho, Ose, Toyoyuki, Fukunaga, Yuko, Okabe, Yuki, Matsumoto, Naoki, Yonezawa, Kento, Shimizu, Nobutaka, Kollnberger, Simon, Kasahara, Masanori, Maenaka, Katsumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6193965/
https://www.ncbi.nlm.nih.gov/pubmed/30337538
http://dx.doi.org/10.1038/s41467-018-06797-8