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Obese subcutaneous adipose tissue impairs human myogenesis, particularly in old skeletal muscle, via resistin-mediated activation of NFκB

Adiposity and adipokines are implicated in the loss of skeletal muscle mass with age and in several chronic disease states. The aim of this study was to determine the effects of human obese and lean subcutaneous adipose tissue secretome on myogenesis and metabolism in skeletal muscle cells derived f...

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Detalles Bibliográficos
Autores principales: O’Leary, Mary F., Wallace, Graham R., Davis, Edward T., Murphy, David P., Nicholson, Thomas, Bennett, Andrew J., Tsintzas, Kostas, Jones, Simon W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6193975/
https://www.ncbi.nlm.nih.gov/pubmed/30337633
http://dx.doi.org/10.1038/s41598-018-33840-x