Cargando…
Obese subcutaneous adipose tissue impairs human myogenesis, particularly in old skeletal muscle, via resistin-mediated activation of NFκB
Adiposity and adipokines are implicated in the loss of skeletal muscle mass with age and in several chronic disease states. The aim of this study was to determine the effects of human obese and lean subcutaneous adipose tissue secretome on myogenesis and metabolism in skeletal muscle cells derived f...
Autores principales: | O’Leary, Mary F., Wallace, Graham R., Davis, Edward T., Murphy, David P., Nicholson, Thomas, Bennett, Andrew J., Tsintzas, Kostas, Jones, Simon W. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6193975/ https://www.ncbi.nlm.nih.gov/pubmed/30337633 http://dx.doi.org/10.1038/s41598-018-33840-x |
Ejemplares similares
-
IL-15 promotes human myogenesis and mitigates the detrimental effects of TNFα on myotube development
por: O’Leary, Mary F., et al.
Publicado: (2017) -
Recent advances and future avenues in understanding the role of adipose tissue cross talk in mediating skeletal muscle mass and function with ageing
por: Wilhelmsen, Andrew, et al.
Publicado: (2021) -
IKK/NF-κB regulates skeletal myogenesis via a signaling switch to inhibit differentiation and promote mitochondrial biogenesis
por: Bakkar, Nadine, et al.
Publicado: (2008) -
IKK/NF-κB regulates skeletal myogenesis via a signaling switch to inhibit differentiation and promote mitochondrial biogenesis
por: Bakkar, Nadine, et al.
Publicado: (2013) -
Role of Akirin in Skeletal Myogenesis
por: Chen, Xiaoling, et al.
Publicado: (2013)