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Expression of the Hutchinson-Gilford Progeria Mutation Leads to Aberrant Dentin Formation

Hutchinson-Gilford progeria syndrome (HGPS) is a rare accelerated senescence disease, manifesting dental abnormalities and several symptoms suggestive of premature aging. Although irregular secondary dentin formation in HGPS patients has been reported, pathological mechanisms underlying aberrant den...

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Detalles Bibliográficos
Autores principales: Choi, Hwajung, Kim, Tak-Heun, Jeong, Ju-Kyeong, Strandgren, Charlotte, Eriksson, Maria, Cho, Eui-Sic
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6193977/
https://www.ncbi.nlm.nih.gov/pubmed/30337599
http://dx.doi.org/10.1038/s41598-018-33764-6