Neurogenin3 phosphorylation controls reprogramming efficiency of pancreatic ductal organoids into endocrine cells

β-cell replacement has been proposed as an effective treatment for some forms of diabetes, and in vitro methods for β-cell generation are being extensively explored. A potential source of β-cells comes from fate conversion of exocrine pancreatic cells into the endocrine lineage, by overexpression of...

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Detalles Bibliográficos
Autores principales: Azzarelli, Roberta, Rulands, Steffen, Nestorowa, Sonia, Davies, John, Campinoti, Sara, Gillotin, Sébastien, Bonfanti, Paola, Göttgens, Berthold, Huch, Meritxell, Simons, Benjamin, Philpott, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6193982/
https://www.ncbi.nlm.nih.gov/pubmed/30337647
http://dx.doi.org/10.1038/s41598-018-33838-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6193982/
https://www.ncbi.nlm.nih.gov/pubmed/30337647
http://dx.doi.org/10.1038/s41598-018-33838-5

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