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Stem cell enriched-epithelial spheroid cultures for rapidly assaying small intestinal radioprotectors and radiosensitizers in vitro

Radiation therapy is one of the main treatment options for many cancer patients. Although high doses of radiation may maximize tumor cell killing, dose escalation is limited by toxicity to neighboring normal tissues. This limitation applies particularly to the small intestine, the second most radios...

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Detalles Bibliográficos
Autores principales: de la Cruz Bonilla, Marimar, Stemler, Kristina M., Taniguchi, Cullen M., Piwnica-Worms, Helen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6194004/
https://www.ncbi.nlm.nih.gov/pubmed/30337664
http://dx.doi.org/10.1038/s41598-018-33747-7