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Plasmid-normalized quantification of relative mitochondrial DNA copy number

Alterations of mitochondrial DNA (mtDNA) copy number have been associated with a wide variety of phenotypes and diseases. Unfortunately, the literature provides scarce methodical information about duplex targeting of nuclear and mtDNA that meets the quality criteria for qPCR. Therefore, we establish...

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Detalles Bibliográficos
Autores principales: Fazzini, Federica, Schöpf, Bernd, Blatzer, Michael, Coassin, Stefan, Hicks, Andrew A., Kronenberg, Florian, Fendt, Liane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6194030/
https://www.ncbi.nlm.nih.gov/pubmed/30337569
http://dx.doi.org/10.1038/s41598-018-33684-5