HPV16-Immortalized Cells from Human Transformation Zone and Endocervix are More Dysplastic than Ectocervical Cells in Organotypic Culture

A major risk factor for cervical cancer is persistent infection with high-risk human papillomaviruses (HPV) which can cause cervical intraepithelial neoplasia. Greater than 90% of cervical cancers develop in the transformation zone (TZ), a small region of metaplastic squamous epithelium at the squam...

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Detalles Bibliográficos
Autores principales: Deng, Han, Hillpot, Eric, Mondal, Sumona, Khurana, Kamal K., Woodworth, Craig D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6194146/
https://www.ncbi.nlm.nih.gov/pubmed/30337615
http://dx.doi.org/10.1038/s41598-018-33865-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6194146/
https://www.ncbi.nlm.nih.gov/pubmed/30337615
http://dx.doi.org/10.1038/s41598-018-33865-2

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