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Interactions Between ABCB1 Genotype and Preoperative Statin Use Impact Clinical Outcomes Among Breast Cancer Patients

Multiple clinical trials investigate statins' effects in breast cancer. The ABCB1 genotype appears to influence statin response and toxicity in the cardiovascular setting. This exploratory study aimed to investigate the interplay between preoperative statin use, ABCB1 genotype, and tumor-specif...

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Detalles Bibliográficos
Autores principales: Tryggvadottir, Helga, Huzell, Louise, Gustbée, Emma, Simonsson, Maria, Markkula, Andrea, Jirström, Karin, Rose, Carsten, Ingvar, Christian, Borgquist, Signe, Jernström, Helena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6194198/
https://www.ncbi.nlm.nih.gov/pubmed/30370250
http://dx.doi.org/10.3389/fonc.2018.00428