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Advances in structure determination by cryo‐EM to unravel membrane‐spanning pore formation

The beta pore‐forming proteins (β‐PFPs) are a large class of polypeptides that are produced by all Kingdoms of life to contribute to their species' own survival. Pore assembly is a sophisticated multi‐step process that includes receptor/membrane recognition and oligomerization events, and is en...

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Detalles Bibliográficos
Autores principales: Scott, Harry, Huang, Wei, Bann, James G., Taylor, Derek J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6194281/
https://www.ncbi.nlm.nih.gov/pubmed/30129169
http://dx.doi.org/10.1002/pro.3454