Mitochondrial replacement therapy and assisted reproductive technology: A paradigm shift toward treatment of genetic diseases in gametes or in early embryos

BACKGROUND: Recent technological development allows nearly complete replacement of the cytoplasm of egg/embryo, eliminating the transmission of undesired defective mitochondria (mutated mitochondrial DNA: mtDNA) for patients with inherited mitochondrial diseases, which is called mitochondrial replac...

Descripción completa

Detalles Bibliográficos
Autores principales: Tachibana, Masahito, Kuno, Takashi, Yaegashi, Nobuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Review Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6194288/
https://www.ncbi.nlm.nih.gov/pubmed/30377395
http://dx.doi.org/10.1002/rmb2.12230

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6194288/
https://www.ncbi.nlm.nih.gov/pubmed/30377395
http://dx.doi.org/10.1002/rmb2.12230

Ejemplares similares