High MDR‐1 expression by MAIT cells confers resistance to cytotoxic but not immunosuppressive MDR‐1 substrates

High expression of the ATP‐binding cassette‐multi‐drug efflux protein 1 (MDR1) is a striking feature of mucosal‐associated invariant T (MAIT) cells, a prominent human innate‐like T cell subset. We demonstrate significantly higher MDR1 expression by CD8 (+) CD161 (++) Vα7.2 (+) MAIT cells than the ph...

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Detalles Bibliográficos
Autores principales: Fergusson, J.R., Ussher, J.E., Kurioka, A., Klenerman, P., Walker, L.J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6194332/
https://www.ncbi.nlm.nih.gov/pubmed/30231297
http://dx.doi.org/10.1111/cei.13165

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6194332/
https://www.ncbi.nlm.nih.gov/pubmed/30231297
http://dx.doi.org/10.1111/cei.13165

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