Doxycycline, an Inhibitor of Mitochondrial Biogenesis, Effectively Reduces Cancer Stem Cells (CSCs) in Early Breast Cancer Patients: A Clinical Pilot Study

Background and objectives: Cancer stem cells (CSCs) have been implicated in tumor initiation, recurrence, metastatic spread and poor survival in multiple tumor types, breast cancers included. CSCs selectively overexpress key mitochondrial-related proteins and inhibition of mitochondrial function may...

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Detalles Bibliográficos
Autores principales: Scatena, Cristian, Roncella, Manuela, Di Paolo, Antonello, Aretini, Paolo, Menicagli, Michele, Fanelli, Giovanni, Marini, Carolina, Mazzanti, Chiara Maria, Ghilli, Matteo, Sotgia, Federica, Lisanti, Michael P., Naccarato, Antonio Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6194352/
https://www.ncbi.nlm.nih.gov/pubmed/30364293
http://dx.doi.org/10.3389/fonc.2018.00452

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6194352/
https://www.ncbi.nlm.nih.gov/pubmed/30364293
http://dx.doi.org/10.3389/fonc.2018.00452

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