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Chimeric Antigen Receptor (CAR) Treg: A Promising Approach to Inducing Immunological Tolerance

Cellular therapies with polyclonal regulatory T-cells (Tregs) in transplantation and autoimmune diseases have been carried out in both animal models and clinical trials. However, The use of large numbers of polyclonal Tregs with unknown antigen specificities has led to unwanted effects, such as syst...

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Detalles Bibliográficos
Autores principales: Zhang, Qunfang, Lu, Weihui, Liang, Chun-Ling, Chen, Yuchao, Liu, Huazhen, Qiu, Feifei, Dai, Zhenhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6194362/
https://www.ncbi.nlm.nih.gov/pubmed/30369931
http://dx.doi.org/10.3389/fimmu.2018.02359