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Activity-based ubiquitin-protein probes reveal target protein specificity of deubiquitinating enzymes

Ubiquitination is an essential eukaryotic post-translational modification that regulates various cellular processes. The removal of ubiquitin from its target protein is catalyzed by deubiquitinating enzymes (DUBs). Although it was proposed that many DUBs specifically interact and recognize ubiquitin...

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Detalles Bibliográficos
Autores principales: Gong, Ping, Davidson, Gregory A., Gui, Weijun, Yang, Kun, Bozza, William P., Zhuang, Zhihao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6194582/
https://www.ncbi.nlm.nih.gov/pubmed/30429995
http://dx.doi.org/10.1039/c8sc01573b