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Microtubule polyglutamylation and acetylation drive microtubule dynamics critical for platelet formation

BACKGROUND: Upon maturation in the bone marrow, polyploid megakaryocytes elongate very long and thin cytoplasmic branches called proplatelets. Proplatelets enter the sinusoids blood vessels in which platelets are ultimately released. Microtubule dynamics, bundling, sliding, and coiling, drive these...

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Detalles Bibliográficos
Autores principales: van Dijk, Juliette, Bompard, Guillaume, Cau, Julien, Kunishima, Shinji, Rabeharivelo, Gabriel, Mateos-Langerak, Julio, Cazevieille, Chantal, Cavelier, Patricia, Boizet-Bonhoure, Brigitte, Delsert, Claude, Morin, Nathalie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6194603/
https://www.ncbi.nlm.nih.gov/pubmed/30336771
http://dx.doi.org/10.1186/s12915-018-0584-6