Unique true predicted neoantigens (TPNAs) correlates with anti-tumor immune control in HCC patients

BACKGROUND: A novel prediction algorithm is needed for the identification of effective tumor associated mutated neoantigens. Only those with no homology to self wild type antigens are true predicted neoantigens (TPNAs) and can elicit an antitumor T cell response, not attenuated by central tolerance....

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Detalles Bibliográficos
Autores principales: Petrizzo, Annacarmen, Tagliamonte, Maria, Mauriello, Angela, Costa, Valerio, Aprile, Marianna, Esposito, Roberta, Caporale, Andrea, Luciano, Antonio, Arra, Claudio, Tornesello, Maria Lina, Buonaguro, Franco M., Buonaguro, Luigi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6194606/
https://www.ncbi.nlm.nih.gov/pubmed/30340600
http://dx.doi.org/10.1186/s12967-018-1662-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6194606/
https://www.ncbi.nlm.nih.gov/pubmed/30340600
http://dx.doi.org/10.1186/s12967-018-1662-9

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