Disrupting USP5/Cav3.2 interactions protects female mice from mechanical hypersensitivity during peripheral inflammation

Cav3.2 T-type calcium channels are important for the signaling of nociceptive information in the primary afferent pain pathway. During neuropathy and peripheral inflammation, Cav3.2 channels are upregulated due to an increased association with the deubiquitinase USP5. Disrupting these interactions i...

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Detalles Bibliográficos
Autores principales: Gadotti, Vinicius M., Zamponi, Gerald W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Micro Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6194615/
https://www.ncbi.nlm.nih.gov/pubmed/30340616
http://dx.doi.org/10.1186/s13041-018-0405-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6194615/
https://www.ncbi.nlm.nih.gov/pubmed/30340616
http://dx.doi.org/10.1186/s13041-018-0405-4

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