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Transplantation, gene therapy and intestinal pathology in MNGIE patients and mice

BACKGROUND: Gastrointestinal complications are the main cause of death in patients with mitochondrial neurogastrointestinal encephalomyopathy (MNGIE). Available treatments often restore biochemical homeostasis, but fail to cure gastrointestinal symptoms. METHODS: We evaluated the small intestine neu...

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Detalles Bibliográficos
Autores principales: Yadak, Rana, Boot, Max V., van Til, Niek P., Cazals-Hatem, Dominique, Finkenstedt, Armin, Bogaerts, Elly, de Coo, Irenaeus F., Bugiani, Marianna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6194683/
https://www.ncbi.nlm.nih.gov/pubmed/30340467
http://dx.doi.org/10.1186/s12876-018-0881-0