Decreases in TGF-β1 and PDGF levels are associated with echocardiographic changes during adjuvant radiotherapy for breast cancer

BACKGROUND: Radiation-induced heart disease is mainly caused by activation of the fibrotic process. Transforming growth factor-beta 1 (TGF-β1) and platelet-derived growth factor (PDGF) are pro-fibrotic mediators. The aim of our study was to evaluate the behavior of TGF-β1 and PDGF during adjuvant ra...

Descripción completa

Detalles Bibliográficos
Autores principales: Aula, Hanna, Skyttä, Tanja, Tuohinen, Suvi, Luukkaala, Tiina, Hämäläinen, Mari, Virtanen, Vesa, Raatikainen, Pekka, Moilanen, Eeva, Kellokumpu-Lehtinen, Pirkko-Liisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6194684/
https://www.ncbi.nlm.nih.gov/pubmed/30340644
http://dx.doi.org/10.1186/s13014-018-1150-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6194684/
https://www.ncbi.nlm.nih.gov/pubmed/30340644
http://dx.doi.org/10.1186/s13014-018-1150-7

Ejemplares similares