Protective role of down-regulated microRNA-31 on intestinal barrier dysfunction through inhibition of NF-κB/HIF-1α pathway by binding to HMOX1 in rats with sepsis

BACKGROUND: Intestinal barrier dysfunction is a significant clinical problem, commonly developing in a variety of acute or chronic pathological conditions. Herein, we evaluate the effect of microRNA-31 (miR-31) on intestinal barrier dysfunction through NF-κB/HIF-1α pathway by targeting HMOX1 in rats...

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Detalles Bibliográficos
Autores principales: Zhan, Cheng-Ye, Chen, Di, Luo, Jin-Long, Shi, Ying-Hua, Zhang, You-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6194748/
https://www.ncbi.nlm.nih.gov/pubmed/30340459
http://dx.doi.org/10.1186/s10020-018-0053-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6194748/
https://www.ncbi.nlm.nih.gov/pubmed/30340459
http://dx.doi.org/10.1186/s10020-018-0053-2

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