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The Pathophysiological Relevance of the iNKT Cell/Mononuclear Phagocyte Crosstalk in Tissues

CD1d-restricted Natural Killer T (NKT) cells are regarded as sentinels of tissue integrity by sensing local cell stress and damage. This occurs via recognition of CD1d-restricted lipid antigens, generated by stress-related metabolic changes, and stimulation by inflammatory cytokines, such as IL-12 a...

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Detalles Bibliográficos
Autores principales: Cortesi, Filippo, Delfanti, Gloria, Casorati, Giulia, Dellabona, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6194905/
https://www.ncbi.nlm.nih.gov/pubmed/30369933
http://dx.doi.org/10.3389/fimmu.2018.02375