Cargando…

Surgical incision induces learning impairment in mice partially through inhibition of the brain-derived neurotrophic factor signaling pathway in the hippocampus and amygdala

Surgical incision-induced nociception contributes to the occurrence of postoperative cognitive dysfunction. However, the exact mechanisms involved remain unclear. Brain-derived neurotrophic factor (BDNF) has been demonstrated to improve fear learning ability. In addition, BDNF expression is influenc...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Zhen, Liu, Fan, Liu, Xiaowen, Ma, Chao, Zhao, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6194924/
https://www.ncbi.nlm.nih.gov/pubmed/30232930
http://dx.doi.org/10.1177/1744806918805902