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Overlapping genes and the proteins they encode differ significantly in their sequence composition from non-overlapping genes

Overlapping genes represent a fascinating evolutionary puzzle, since they encode two functionally unrelated proteins from the same DNA sequence. They originate by a mechanism of overprinting, in which point mutations in an existing frame allow the expression (the "birth") of a completely n...

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Detalles Bibliográficos
Autores principales: Pavesi, Angelo, Vianelli, Alberto, Chirico, Nicola, Bao, Yiming, Blinkova, Olga, Belshaw, Robert, Firth, Andrew, Karlin, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6195259/
https://www.ncbi.nlm.nih.gov/pubmed/30339683
http://dx.doi.org/10.1371/journal.pone.0202513