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Overlapping genes and the proteins they encode differ significantly in their sequence composition from non-overlapping genes
Overlapping genes represent a fascinating evolutionary puzzle, since they encode two functionally unrelated proteins from the same DNA sequence. They originate by a mechanism of overprinting, in which point mutations in an existing frame allow the expression (the "birth") of a completely n...
Autores principales: | Pavesi, Angelo, Vianelli, Alberto, Chirico, Nicola, Bao, Yiming, Blinkova, Olga, Belshaw, Robert, Firth, Andrew, Karlin, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6195259/ https://www.ncbi.nlm.nih.gov/pubmed/30339683 http://dx.doi.org/10.1371/journal.pone.0202513 |
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