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Ensemble of machine learning algorithms using the stacked generalization approach to estimate the warfarin dose

Warfarin dosing remains challenging due to narrow therapeutic index and highly individual variability. Incorrect warfarin dosing is associated with devastating adverse events. Remarkable efforts have been made to develop the machine learning based warfarin dosing algorithms incorporating clinical fa...

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Detalles Bibliográficos
Autores principales: Ma, Zhiyuan, Wang, Ping, Gao, Zehui, Wang, Ruobing, Khalighi, Koroush
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6195267/
https://www.ncbi.nlm.nih.gov/pubmed/30339708
http://dx.doi.org/10.1371/journal.pone.0205872