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Ensemble of machine learning algorithms using the stacked generalization approach to estimate the warfarin dose
Warfarin dosing remains challenging due to narrow therapeutic index and highly individual variability. Incorrect warfarin dosing is associated with devastating adverse events. Remarkable efforts have been made to develop the machine learning based warfarin dosing algorithms incorporating clinical fa...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6195267/ https://www.ncbi.nlm.nih.gov/pubmed/30339708 http://dx.doi.org/10.1371/journal.pone.0205872 |