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Human αB-crystallin as fusion protein and molecular chaperone increases the expression and folding efficiency of recombinant insulin

Low expression and instability are significant challenges in the recombinant production of therapeutic peptides. The current study introduces a novel expression and purification system for human insulin production using the molecular chaperone αB-crystallin (αB-Cry) as a fusion partner protein. Insu...

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Detalles Bibliográficos
Autores principales:	Akbarian, Mohsen, Yousefi, Reza
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6195290/ https://www.ncbi.nlm.nih.gov/pubmed/30339677 http://dx.doi.org/10.1371/journal.pone.0206169

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