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Calcium-dependent electrostatic control of anion access to the pore of the calcium-activated chloride channel TMEM16A
TMEM16A is a ligand-gated anion channel that is activated by intracellular Ca(2+). This channel comprises two independent pores and closely apposed Ca(2+) binding sites that are contained within each subunit of a homodimeric protein. Previously we characterized the influence of positively charged po...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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eLife Sciences Publications, Ltd
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6195346/ https://www.ncbi.nlm.nih.gov/pubmed/30311910 http://dx.doi.org/10.7554/eLife.39122 |