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Mutant TP53 modulates metastasis of triple negative breast cancer through adenosine A2b receptor signaling

PURPOSE: The identification of genes with synthetic lethality in the context of mutant TP53 is a promising strategy for the treatment of basal-like triple negative breast cancer (TNBC). This study investigated regulators of mutant TP53 (R248Q) in basal-like TNBC and their impact on tumorigenesis. EX...

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Detalles Bibliográficos
Autores principales: Horigome, Eisuke, Fujieda, Michiru, Handa, Tadashi, Katayama, Ayaka, Ito, Masashi, Ichihara, Ami, Tanaka, Daiki, Gombodorj, Navchaa, Yoshiyama, Shinji, Yamane, Arito, Yamada, Keiichi, Horiguchi, Jun, Shinozuka, Kazuo, Oyama, Tetsunari, Nishiyama, Masahiko, Rokudai, Susumu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6195371/
https://www.ncbi.nlm.nih.gov/pubmed/30349649
http://dx.doi.org/10.18632/oncotarget.26177