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Mutant TP53 modulates metastasis of triple negative breast cancer through adenosine A2b receptor signaling
PURPOSE: The identification of genes with synthetic lethality in the context of mutant TP53 is a promising strategy for the treatment of basal-like triple negative breast cancer (TNBC). This study investigated regulators of mutant TP53 (R248Q) in basal-like TNBC and their impact on tumorigenesis. EX...
Autores principales: | Horigome, Eisuke, Fujieda, Michiru, Handa, Tadashi, Katayama, Ayaka, Ito, Masashi, Ichihara, Ami, Tanaka, Daiki, Gombodorj, Navchaa, Yoshiyama, Shinji, Yamane, Arito, Yamada, Keiichi, Horiguchi, Jun, Shinozuka, Kazuo, Oyama, Tetsunari, Nishiyama, Masahiko, Rokudai, Susumu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6195371/ https://www.ncbi.nlm.nih.gov/pubmed/30349649 http://dx.doi.org/10.18632/oncotarget.26177 |
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