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Surrogate endpoints in advanced sarcoma trials: a meta-analysis

BACKGROUND: Alternative endpoints to overall survival (OS) are frequently used to assess treatment efficacy in randomized controlled trials (RCT). Their properties in terms of surrogate outcomes for OS need to be assessed. We evaluated the surrogate properties of progression-free survival (PFS), tim...

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Detalles Bibliográficos
Autores principales: Savina, Marion, Litière, Saskia, Italiano, Antoine, Burzykowski, Tomasz, Bonnetain, Franck, Gourgou, Sophie, Rondeau, Virginie, Blay, Jean-Yves, Cousin, Sophie, Duffaud, Florence, Gelderblom, Hans, Gronchi, Alessandro, Judson, Ian, Le Cesne, Axel, Lorigan, Paul, Maurel, Joan, van der Graaf, Winette, Verweij, Jaap, Mathoulin-Pélissier, Simone, Bellera, Carine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6195375/
https://www.ncbi.nlm.nih.gov/pubmed/30349653
http://dx.doi.org/10.18632/oncotarget.26166