3’Igh enhancers hs3b/hs4 are dispensable for Myc deregulation in mouse plasmacytomas with T(12;15) translocations

Myc-deregulating T(12;15) chromosomal translocations are the hallmark cytogenetic abnormalities of murine plasmacytomas (PCTs). In most PCTs, the immunoglobulin heavy chain (Igh) locus is broken between the Eμ enhancer and the 3’ regulatory region (3’RR), making the latter the major candidate for or...

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Detalles Bibliográficos
Autores principales: Kovalchuk, Alexander L., Sakai, Tomomi, Qi, Chen-Feng, Du Bois, Wendy, Dunnick, Wesley A., Cogné, Michel, Morse, Herbert C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6195379/
https://www.ncbi.nlm.nih.gov/pubmed/30349647
http://dx.doi.org/10.18632/oncotarget.26160

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6195379/
https://www.ncbi.nlm.nih.gov/pubmed/30349647
http://dx.doi.org/10.18632/oncotarget.26160

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