Characterization of murine CEACAM1 in vivo reveals low expression on CD8(+) T cells and no tumor growth modulating activity by anti-CEACAM1 mAb CC1

Carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1) has been reported to mediate both tumorigenic and anti-tumor effects in vivo. Blockade of the CEACAM1 signaling pathway has recently been implicated as a novel mechanism for cancer immunotherapy. CC1, a mouse anti-CEACAM1 monoclonal...

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Detalles Bibliográficos
Autores principales: McLeod, Robbie L., Angagaw, Minilik H., Baral, Toya Nath, Liu, Liming, Moniz, Raymond Joseph, Laskey, Jason, Hsieh, SuChun, Lee, Mike, Han, Jin-Hwan, Issafras, Hassan, Javaid, Sarah, Loboda, Andrey, Sadekova, Svetlana, O'Connor, Joann A., Tse, Archie, Punnonen, Juha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6195382/
https://www.ncbi.nlm.nih.gov/pubmed/30349641
http://dx.doi.org/10.18632/oncotarget.26108

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6195382/
https://www.ncbi.nlm.nih.gov/pubmed/30349641
http://dx.doi.org/10.18632/oncotarget.26108

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