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miR4673 improves fitness profile of neoplastic cells by induction of autophagy
Therapeutic resistance of neoplasms is mainly attributed to gradual evolution of mutational profile(1). Here, we demonstrate a microRNA-mediated mechanism that effectively improves fitness of SKBR3 mammary carcinoma cells by cytoplasmic reprogramming. The reprogramming is triggered by endogenous miR...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6195512/ https://www.ncbi.nlm.nih.gov/pubmed/30341280 http://dx.doi.org/10.1038/s41419-018-1088-6 |